For drugs commonly used in various species for tranquilization, sedation, or analgesia, see Table: Dosage of Tranquilizers and Sedatives without Analgesic Effects and see Table: Dosage of Analgesics.
In fact, it is estimated that approximately 1 in 100,000 animals will have some sort of reaction to an anesthetic agent.
Reactions can range from mild to severe and include a wide variety of symptoms, such as swelling at the injection site to more serious outcomes such as anaphylactic shock or death.
Tranquilization reduces anxiety and induces a sense of tranquility without drowsiness.
Drug-induced sedation has a more profound effect and produces drowsiness and hypnosis.
These patients die most commonly as a consequence of struggling and stress!
I once actually witnessed the death of a cardiomyopathic Doberman who struggled and went into ventricular fibrillation while being restrained for an EKG; the owner watched the whole thing!A patient in severe respiratory distress is at risk of death as a consequence of minimal diagnostic or therapeutic interventions, but is also at risk if you do nothing; it would be well to advise your client of this at your initial contact!I have a great deal of experience with this situation, and strong convictions as well.Analgesia is the reduction of pain, which according to a drug’s effect, may be more pronounced in either the viscera or the musculoskeletal system (see Pain Assessment and Management).Many drugs cannot be categorized by only one pharmacologic effect, ie, as tranquilizers, sedatives, or analgesics.While there is always an exception to the rule, appropriate sedation is my preference for handling these patients, hands down! before radiographs, IV catheter, thoracocentesis, echocardiogram, etc.